Obstructive Sleep Apnea and Diabetic Nephropathy A cohort study
نویسندگان
چکیده
RESEARCH DESIGN AND METHODSdThis was a cohort study in adults with type 2 diabetes. Patients with known OSA or ESRD were excluded. DN was defined as the presence of albuminuria or an estimated glomerular filtration rate (eGFR) ,60 mL/min/1.73 m. DN progression was based on eGFR measurements. OSA was defined as apnea hypopnea index (AHI) $5 events/h. Serum nitrotyrosine abundance (a marker of nitrosative stress) was measured by ELISA.
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